Creative Biogene Expands Antibody Purification Platform for Biotechnology Research

Creative Biogene has expanded its antibody purification platform to provide biotechnology researchers and companies with a comprehensive solution for producing high-yield, high-purity antibodies through scalable and customizable protocols. The platform addresses the critical need for consistent and efficient antibody preparations across various research and development applications, from antibody candidate development programs to assay optimization and production of research reagents. The purification workflow incorporates multiple stages including capture, intermediate, and polishing steps, utilizing Protein A/G/L resins for Fc-binding antibodies and offering ion exchange chromatography for charge-based purification. Size exclusion chromatography effectively removes aggregates, ensuring final antibody purity exceeding 95%. The platform also features orthogonal processes such as hydrophobic interaction chromatography and multimodal approaches, complemented by comprehensive quality control services including SDS-PAGE, SEC-HPLC, and endotoxin testing with results delivered in detailed Certificate of Analysis reports.

Supported by a range of specialized equipment, the platform includes compact chromatography columns, process chromatography systems available at laboratory and pilot scales, and advanced filtration systems including tangential flow and depth filtration options. Buffer dilution and conditioning systems enable precise formulation while minimizing resource consumption, contributing to the platform's efficiency and environmental sustainability. The system's design allows for fast turnaround between purification runs, enhancing productivity for research institutions and biotechnology companies. According to Marcia Brady's Chief Expert, the platform's main value lies in its well-balanced throughput and reproducibility, having been optimized to deliver consistent results across various scales and antibody targets. This reliability enables researchers to streamline their work processes while maintaining high quality standards. The platform's flexibility makes it suitable for diverse biotechnology applications, supporting the development of therapeutic antibodies, diagnostic components, and research reagents.

Creative Biogene continues to invest in platform improvements, with plans to incorporate additional automation features and enhanced scalability through future integration and refinement of purification protocols. The company's commitment to advancing purification technology aligns with the biotechnology industry's evolving needs for reliable, accessible resources that support scientific discovery and innovation. For technical specifications and service details, researchers can access information through the company's official website.